1. Why should we look back to move forward in modern healthcare?
2. Is the Paleo Solution your species real solution?
3. How would have evolution had to build a human brain based upon what we know today?
4. How does lipid chemistry destroy the Savanna Hypothesis with some new knowledge we have in brain chemistry?
5. Will you Epi-Paleo it forward now that you have a deeper understanding how that 3 pounds of jelly works best in your head?
The paleo community has the “Paleo Solution“, and it is a great introductory book to a lifestyle that will improve people to a higher plane of health than we have while eating a standard American diet found in our western world. It is clear from fossil data humans were in better physical shape in the late paleolithic before the Younger Dryas occurred as well. It appears that this deep freeze caused massive dietary change in the homo species from predominate hunter gatherers culture to and agrarian culture because of rapid climate change and elimination of the great megafauna from our food chains. The focus of this series, however, is focused upon when we jumped from purely primate to mainly homo species and to see what diet is really best for the rapid encephalization of our species. I am not convinced the modern paleolithic diet that is quite popular now fits that bill at all. The reason I bring this forth, is because I treat very sick and ill homo sapiens every day. ’Eating paleo’ may just NOT reverse their health. The proof of this is found on every single popular paleo forum you can visit. As a surgeon, I need something that really works in the most resistant cases. That is where I discovered the Epi-Paleo Rx.
In my specialty of spine surgery, this is especially true when we are dealing with cranial and spinal pathology. As a neurosurgeon these neolithic diseases are the ones I am most focused in on in my clinic. Evolution is in large part about epigenetic to cellular communication; it’s comparing notes and copying and pasting new genetic recipes to create a new dish. When we understand how that dish was created we gain deep insight of how to to keep that dish tasting crisp and fresh every time we replicate it.
For this reason, I think we must look back in time to when this transition occurred about 2.6-2.5 million years (mya) when massive climatic shifts occurred in the East African Rift that I laid out in Brain Gut 3. When we go back to the milieu that transitional man found himself in we might gain some insight to learn something about how to really reverse the neolithic diseases all physicians are seeing in their clinic daily. If these forces were strong enough to form us from ape they may hold the keys to what is optimal for our current biology with respect to our guts and our brains. The assault of these diseases to me is akin to an “unending tsunami waves” hitting our shores since the Younger Dryas forced homo to rely on sub-optimal food sources to just survive.
After my Factor X webinar, people learned that the currency of survival for all eutherian mammals was a new biologic strategy to speed up DNA expression to adapt more quickly to the environment. The reasons eutherian mammals survived is because they use a placenta to birth their young. There is now strong evidence from molecular biology that the genes that coded for the evolution of the placenta were heavily selected for after the K-T event. How do we know this? The first mammals were rather old in an evolutionary scale, about 210 x10 to the 6th years before the present time (YBP). These early mammals (such as multituberculates) were small, furry, egg-laying, monotreme-like insect predators. They were present prior to the advent of the dinosaurs, but became extinct about 35 x 10 to the 6th YBP. We know nothing about their molecular genomes, but what we do know, is that two other mammalian lines developed from them directly, the marsupials and the eutharian placentals. Humans are in the later class. How do we know placenta were heavily selected by a post K-T world? Well, the marsupials are only found in the southern hemisphere with the few exceptions. This fits perfectly with how Factor X occurred 65 million years ago as well as I laid out in my Webinar. Moreover, the placental mammals were far more successful because they radiated over 2000 genera, to about only 140 genera in the marsupial clade.
Most of the surviving species left on the land of this planet is due to that formative moment in evolution. This is a big step in knowing who we really are and how we are built. Factor X is huge for any mammal that evolved after it.
HOW DOES VIRAL MARKETING, CT, FACTOR X, AND CT-6 ALL COME TOGETHER FOR HOMO’S SOLUTION?
Here is the most important fact in all of mammalian evolution in my opinion that is not talked about enough. With these placental mammals, we see clear and compelling patterns of acquisition of genetic parasitic elements in their genomes, mainly in the context of retroviruses like LINES, SINES, and ERVS. After K-T the best source of food was located in the deep polar seas with its huge collection of marine life and cauldron of viral particles as we covered in Brain Gut 2. The predominate macronutrient in the sea is seafood/microalgae.
This means that all the animals left on our planet at some point after the K-T event would of had their food supply tied to the ocean as some point. This is a massive link in the Quilt.
It was also bitter cold for many years after a sudden global event like K-T impact. What would life do in this case like this? It would have to evolve to that environment rapidly and that is precisely what happened to our deepest ancestors by using viral marketing as laid out in Brain Gut 2. That program is wired into the neural structures of every surviving animal left on the planet. This was my thought process when I was thinking about finding the Ancient Pathway in the mammalian brain I laid out in CT-6 blog post. I think it is no coincidence that eutherian mammals 65 million years ago and modern man 13,000 years ago had to navigate the same freezing environment and survive. Clearly, this ancient program was wired into the mammalian nervous system for a deep evolutionary reason.
Let us now fast forward to 2.6 million years ago where our recent ancestors come from, the transitional apes. I have already showed you in Parts 1-3 of this series that primates and humans use massive amounts of these transposable genetic elements to create new genes to adapt quickly. What do you think transitional ape used to become man?
Evolution uses a fractal design where form always meets function, of course, and we did the very same thing again in our speciation as life did after the K-T event.
FACTOR X AND NEOLITHIC DISEASE GENERATION:
Many people wanted to know what they could do to their human biology to make Factor X work for them to reverse the curse of neolithic disease. In my opinion, this series is that first and most important step in that direction. To know who you are, you must first know where you came from. This is the key point in Brain Gut 1. Moreover, you need to know precisely why it happened to make it actionable. Why you ask? Because it tells you where you might be headed if you fall off the path that brought your existence to life.
Today our species has fallen way off that track. That is why humans today are mediocre as a species and are in current decline morphologically and neurologically. Moreover, we are becoming more feeble and useless as we age because of how broken we are metabolically from a physiologic stand point. This is really evidenced in the diseases of the brain and the gut of modern man. They are catastrophe’s in both size and scope, and not to mention cost. It’s why modern medicine needs a new perspective, because they don’t know how and why we evolved. This is where biology’s epistemologic foundation lies. Modern healthcare is blind to this very fundamental fact. This is why we are poor in healing chronic diseases.
In my view, when you use evolution as your North Star…….you get a lot smarter about how to best treat chronic disease we see today.
What happened in Africa at the transition from ape to man?
1. We had retreating forests in the middle of Africa and the opening of the grass lands we see today.
2. We lost a lot of megfauna
3. We began to see a lot new speciation and genera’s show up in the bone collector’s fossil data
4. We begin to see stone tools in archeology
5. We see Homo Habilis show up in the bone collector’s data
6. We immediately see rapid changes in the Homo’s feet from apes
7. We see major changes in the morphology of Homo’s spines, pelvis, and hind limb
8. We begin to see rapid encephalization of Homo
10. The geology of the tectonic plates in the Rift Zone raised the continent while cooling it and making the interior drier while the sea levels rose on the coast. This is the first time transitional apes like had the introduction to sea based water as a common environmental component to their life cycle. The skeletons of Lucy and Ardi told the bone collectors clearly that we did not come from the Savanna. Water was somehow tied to our evolution because of one special adaptation we had……..a brain that requires water constantly. Even today, most evolutionary experts are blind to this fundamental fact.
Why was water tied to our evolution?
The answer to me was pretty simple and straight forward. Construction of the human brain, itself is that answer. You can’t do it without a food chain tied to the ocean at some level. Many evolutionary experts still refute this today. In my opinion, if you refute this you will never reverse or avoid any neolithic disease. I will show you why that is the case in the remainder of this blog. None of what I am going to share with you is my invention. These are scientific facts we know are true. My part is to show you how they all fit together to create an optimal human to avoid disease and illness.
The brain separates humans from all other mammals. It gives us much of uniqueness and it controls most of our physiology at a basic level. The brain is an organ I have an intimate relationship with as a neurosurgeon. I have spent over 40 years of my life studying it. It has some special features in its membranes that make it awfully special to biology, and to evolution. It is made up of an excitable membranes filled with fats and phospholipids that have one main source on this planet. That source is the ocean. The savanna does not have these sources to support Lucy having a 189 cm cubed cerebral volume to Homo Habilis cerebral volume of 640 cm cubed. The brain is made up of long chained polyunsaturated fatty acids (0mega3 PUFA) called docosahexaennoic acid (DHA). To make make a three pound human brain you need a lot of DHA. DHA is found in seafood and microalgae in the oceans at the coasts of land. DHA is also the one constant building block in the nervous systems of all living things. Here is another queer finding about the impact of DHA. In mammals eating a terrestrial diet low in DHA and (Arachadonic acid) AA, from small to large mammals, brain size decreased with one major exception……US!
Humans are the real curve breaker. You have to begin to ask yourself why we do not follow the normal DHA/EPA brain plan if we came from the Savanna? We also know that humans migrated out of Africa using coastal waterways to the rest of the world. The bone collectors have always been puzzled by the lack of hominid fossils found but I have not been. Why is that? Two reasons stand out to me most. If we evolved quickly, as I believe we have, there would not be a lot of transtional fossils. The second point is about sea water. Bones cant stay preserved in sea water over time. They dissolve! So if our evolution occurred around sea water, it would have completely destroyed the bone evidence over time quickly. To date the hominid fossil record between small brained transitional apes and large brained homo is pretty damn poor. You would think these reasons would be intuitive to a bunch of bright bone collectors but it was not and remains a dead subject to most of their dogma. Are all these facts coincidence or not?
See when you are faced with a paradox it can stump you or you can make a theory up about how your beliefs about where we came from should dominate. That is called the Savanna Hypothesis. These facts should make you wonder who might be correct or not about our genesis. You decide. I already have for me and my patients. And this is why my patients get better from chronic illness now. I have a new perspective on where we came from and how our blueprint is designed to work. It is not a primal blueprint you were told about in a paleo book either……..it is a marine blueprint.
DOES SIZE MATTER?
Using a modern ape to present day human brain size is analogous to comparing the economy of Rhode Island to that of the United States. The bone collectors have a neat way to calculate cranial expansion in fossils. They call it the encepalization quotient (EQ). They are expressed in % compared to modern homo sapiens relative brain sizes. Lucy falls at 46% and Homo Habilis falls at 53%. Homo Habilis is the only transition mammals that has an EQ over 50%. This happened in less than 2 million years. Modern man’s brain is moving toward Habilis and away from its largest weight we had just 20,000 years ago even today! Yes, our brain is shrinking back to our transitional ape ancestery because of how we eat today. It seems no one is realizing this is happening right under our noses.
The other striking variable that one has to also factor in these ideas of mine here, is the tectonic shifts in the land massively altered the water tables of Homo’s cradle. This would have dramatically changed the water resources available to Lucy and her kind. The rising plates and cooling and drying on the interior would have favored seaside runoff and reversals of the rivers flow in places. Without any coastal forests in the Rift Zone to retreat too, water would have become the easiest resource to find high density food sources. Moreover, fresh water, not sea water, would have been a real commodity to a transitional ape because they can’t survive without it because of their encephalizing brain. Homo’s are required to drink a lot of fresh water to just survive so their explosive growth suggests that they had to have superior fresh water supplies as well. Moreover, even the famous bone collector, Louis Leaky said this in 1968, when they were plotting where to look for early hominid remains. It is not really controversial now unless you are dogmatic.
So in a few million years we went from very small brains to massive brains in the blink of eye. How did this happen? The speed of transformational change implied at least to me, a few things. What were those things?
One, we had to have a massive source of DHA to fuel encephalization.
Two, we had to have a reliable way to get the DHA into our systems to assimilate it.
Three, we had to have a way to exploit the massive reservoir of DHA to alter our genes to change the chimp brain to a human one.
Four, there had to be a massive source of genetic components to radically change the chromosomes and the genome to shuffle the deck to get a brain.
Five, to support a massive cranial infrastructure transformation, there would have to be massive changes to the mammalian skeletal body plan before encephalization could proceed.
Sixth, reproduction would have to be resort to birthing a more immature progeny with a moldable cranial vault.
Seventh, if the progeny was immature that meant that cooperation would be required via communicative abilities that transitional apes did not possess. If this were not present, reproductive fitness would extinguish our kind before we got started building a brain.
HOW DO YOU BUILD A HUMAN BRAIN FROM A TRANSITIONAL APE?
There are other some key players in building a human brain. You need a ton of Arachadonic acid (AA). This is an omega 6 PUFA. DHA and AA make up 8-10% of the human brain by dry weight. Most of the brain weight mass is from water content. The other key building block of brain building is eicosapentaenoic acid (EPA). AA plays a role for the structure and the functional parts of the brain. DHA is critical in brain structure and EPA plays a functional role in the human brain. Many biochemists and paleoanthropologist believe even to this day, you could make all these three building blocks of the brain from their parent precursors linoleic acid (LA) and Alpha Linolenic acid (ALA). But humans and apes do not have the metabolic machinery to do these conversions in sufficient amounts to make the size brain we have had for the last 200,000 years. It means it is biologically impossible.
That one fact alone should have destroyed the savanna hypothesis, but it did not for many of the bone collectors. Getting rid of dogma is tough business in any branch of science. Then many paleolithic diet supporters (Cordain and the expensive tissue hypothesis folks) said we could build a brain using animal meat alone found on the savanna alone without any seafood/microalgae sources.
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