READERS SUMMARY: 1.  WHY DO MANY HAVE A PROBLEM WITH KETOSIS? 2.  HOW DOES SEASONAL AFFECTIVE DISORDER EXPLAIN THIS PHENOMENA? 3.  HOW DOES TECHNOLOGY SHORT CIRCUIT OUR MITOCHONDRIA? 4.  DO YOU CONFUSE DYSFUNCTION WITH IMMATURITY? 5.  CAN AN IMPERFECT HYPOTHESIS STILL BE DIRECTIONALLY ACCURATE?   Why do I have problems with ketosis?  This is a question I get asked a lot and a question I see asked in many other places online.  The answer isn’t an obvious one.  Most people think ketosis is a function of the amount of fat or protein you eat.  It is not.  The best brand of ketosis is the one that allows our brain and mitochondria to sense the correct circadian signals from our environment.  You have to have your circadian cycles and your food match or yoked to understand the context correctly.  Ketosis without water is a losing strategy.  Water remains in cells when the the voltage gated channels are working well.  This requires iodine and DHA in cell membranes.  If you only look at one and not the other it is akin to having one oar in a row boat.  You will spin in circles until you realize both need to match.  Ketosis […]

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EMF Rx: The Top Ten EMF FAQs

Soon the EMF Rx will go live in our March 2013 webinar so in advance of it, I wanted to give the EMF FAQ’s for everyone to review before you listen to the webinar. I expect there to be many questions once the webinar is released. Hopefully this will answer many of the questions you might have as the series moves forward.

These may make a lot more sense once you listen to the EMF Rx in the webinar. They will really sink in after you hear our EMF expert that we are bringing on to the site for an extensive long term look at the different aspects that EMF causes in our modern world, but here is an appetizer of what is coming.

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I believe your “health estate plan” must incorporate a “learn by doing” framework. If you want to improve your former self , spend six months volunteering in a hospital making connections with doctors and healthcare workers and see what you learn about their industry. You might find out that few people actually get better despite the actions of many to help them do just that. Hopefully this will make you curious whether as to what you might consider doing to improve your own health than what you are currently doing. You are the only one who has your best interests at heart. If you are not good enough for your time, who are you really good for?

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Cold Thermogenesis 13: The FAQ’s

The readers of my forum asked for a FAQ’s on CT and I decided it would be a good idea to make a short blog about this. They picked their top 25 questions and I decided to answer them for this blog. If you have any others, just ask in the comments section. I answer them all when I have time.

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Cold Thermogenesis 6: The Ancient Pathway

The best way to describe this pathway to the lay public is to explain this is how evolution allows for ideal form to meet function in a tough environment. This environment is likely the primordial environment for life on our planet. This makes astrophysicists excited, because life might also be evolving in places like Titan. After all 5 extinction events on this planet geologist have told us they were followed by an extended cold climate. In cold mammals live longer. You will find out more about why this happens in Energy and Epigenetics 4 and 5 blog posts.

The pathway uses very little energy from ATP and gives a whole lot to the organism who uses it. Fat burning is required and it is tied to a biochemical pathway that paleo forgot to speak about. But it requires cold temperature to be present and used commonly. In the pathway, the less effort you give, the faster and more powerful you will be when this pathway is active. People who live in this pathway can run a marathon with no training. They can lift unreal amounts of weight with little training. Their reserve and recovery are just incredible. You have to see it to believe it. Many will say cold thermogenesis a hormetic process, when in reality it is created using a coherent energy source due to something called the Hall effect. When we have had extinction events on Earth before, the events usually affect the evaporation of water in some fashion from the surface of lakes and oceans. It also affects the transpiration from the forest trees, plants, and flowers and this change cools the air. You must understand how climatology works here; liquid water needs to absorb a lot of latent heat to in order to evaporate, so it sucks energy from the atmosphere to make this energy transfer. This loss of energy from the atmosphere directly cools the planet and this preserves the charge on life’s inner mitochondrial membrane and in the nanotubes present in our cells that contain water. This is how life lives long in the cold.

Those people don’t realize this because they do not live in this pathway for the majority of their life, and few studies have been done to say otherwise. The link above is recently added to this blog post. It seems science is now proving me correct in my theories of extinction events.

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Cold Thermogenesis 4: The Holy Trinity

I just want to thank Sean Croxton for asking me to present at Paleo Summit today. The ideas discussed began with a podcast I did with Jimmy Moore, #474. Before I begin here today, I strongly suggest you listen to the Jimmy Moore podcast I did in May of 2011 as a primer for this blog post. It’s going to be a long one, so open a glass of wine as the sun sets tonight. However, I think you need to hear it all tonight since I have your attention from the Paleo Summit. I have planned for this day for some time. I am humbled to share this with you all. It was hard for me to write.

If any of you remember when I first gave my initial thoughts on leptin publicly, it was on a podcast I did with Jimmy Moore in May 2011. I discussed the things that transformed my thinking back then. Most of the time I spent with Jimmy, we talked about leptin. In the beginning of the podcast, I mentioned a person who saw me injure myself as I stood up to give a lecture, and told me she knew precisely why I hurt my knee. At the time, I thought I had a good handle on these modern medicine principles she mentioned so I was a skeptical of her thoughts. She told me when I got home she was going to send me a few papers and a book to read. The book was called “The Monk Who Sold his Ferrari.” She was emphatic that I read the book before the papers. Then, she told me to read six specific papers in the order they were numbered and then reflect on what I had just read.

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The Cold Thermogenesis Protocol

The Cold Thermogenesis Protocol should be added gradually to the Leptin Rx rest protocol. This blog post is additive to the Leptin Rx, and is an evolution extension of it for those who need it. I hope you all realize that not everyone will need it. Some will need it because they have special needs that they face. This blog is designed for those who have been previously left out of the reset protocol. Those people are gastric bypass patients, HCG users, those on exogenous steroids, chronic pain patients, and those with T2D and metabolic syndrome, as a few examples.

Prolonged and controlled local peripheral skin cooling can induce selective “damage,” and increased hypothalamic signaling by forcing adipocyte apoptosis and subsequent loss of subcutaneous fat without damaging the overlying skin or the underlying muscle layers. This means that acute cold cause rapid leptin sensitivity! It means that fat is forced to liberate leptin from fat cells to slowly lower its serum levels as long as the cold stimulus is applied safely. This is new scientific information that was first carried out in pigs in 2008, and subsequently tested in humans and found to be quite effective for fat removal in certain selected areas of the body.

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Rewiring The Leptin Rx Reset

Evolutionary strategy is based upon finding an environmental niche and exploiting it. Evolution is based upon change and the natural adaptations to it. Today, we are going to explore how some environmental triggers might open a “biochemical trap door” that will allow me to add a new recommendation for you to consider adding to the Leptin Rx reset protocol for those who are LR.

I am beginning a series on circadian biology to show you how this all ties in together. Today, I will give you a very cursory review of why circadian biology, leptin, and environment are critical to using the Quilt to obtain your Optimal life.

Why is circadian biology critical to humans?

For evolution to work Optimally, a cell first must adapt to its environment. The first situation any living cell would be subjected to in an earth day is a period of day and night. Over time it would also be subject to the seasons in our environment because of the earth’s revolution, tilt, and angulations of the sun. As time continued on, further life would have been subjected to solar variations and would have had to account for it. It also has to find food to make energy (ATP) to survive, and it also has to control its own cellular division. The epic battle for the cell is to have the regularly expected circadian cycles found in our environment and ”yoke” those signals to its metabolic cycle and to its growth cycle. Most people know that the suprachiasmatic nucleus (SCN) in the brain is where the circadian pacemaker lies in humans. It monitors this dance between darkness and light, and the seasonal cold and hot temperatures in our environment to help control and monitor our own growth and development. Evolution apparently agreed to use these signals in all living things because this is what it uses for all life on earth today. What most people do not know is how leptin plays a massive role in regulating it. Many people and physicians think it plays a small role. Recent research has revealed that leptin can induce expression of a neuropeptide called vasoactive intestinal peptide (VIP) through the VIP cytokine response element. This is an epigenetic modification from our environment directly signaling the master hormone in our body. So what does VIP actually do?

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READERS SUMMARY: ARE THE SUPPLEMENTS FOR THE LEPTIN RESET DIFFERENT FOR HCG USERS? WHAT ARE THOSE SUPPLEMENTS? WHAT DO THOSE SUPPLEMENTS DO? WHAT SHOULD HCG USERS CONSIDER OVER A STANDARD PALEO/PRIMAL TEMPLATE? I decided to add this post for the many readers I have that use HCG. To say that I have been inundated with emails about this topic would be an understatement. I think from my public comments at MDA and PaleoHacks about HCG, people have wanted to know a bit more about why HCG patients react differently than a regular paleo patient would. I think is best explained by the following example. Patients given coumadin by their doctors have to be treated differently for osteoporosis in my clinic. Most of you know I no longer use the bisphosphonate drugs as a first line treatment for this condition. So if a patient is on coumadin, I cannot offer them high dose Vitamin K2 therapy because coumadin depletes vitamin K as a side effect of its mode of action. This why so many people on long term coumdin treatment suffer from dystrophic calcification of their arteries in their aortic tree and coronary vessels while simultaneously having extreme osteopenia. So these […]

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What Are The Optimizing Labs?

When you finally decide to take total control of you life and optimize yourself I always suggest testing. Many of you have bombarded my email and my twitter account for a blog to a list of those labs. Well, today’s post is for you. I was resistant to do this because I felt having the list of labs is a waste of time if you don’t have a physician who can decipher what they all mean for you. 7 years ago, I could not tell you what this group of labs meant at all to your optimal health. I learned it by reading and going to classes to optimize myself. After much reflection I have decided to give you what you asked for. I am fortunate because many of the PCP’s I work with understand these tests well. I may also update it as I think it needs to be updated over time.

The first set of labs are what I call the core lab set for optimization. There are other panels I add to the core lab based upon the history, physical, and the food logs I will have patients give me. This blog is meant to be a resource for you to refer back to when the need arises. Discuss these with your doctor but don’t assume they will run out to order them because they may not know what all these tests will tell them. That part takes some time. I recommend starting the dialogue with your doctor to assess their willingness to help you. Most of my PCP doctors are awesome “helpers” to their patients with these issues. This requires a lot of work on the doctors part and the patients part. Do not be surprised if this is not covered by insurance. The time required to optimize someone is unreal. I know how long I spent optimizing myself 6 years ago. It was a tedious process but I was not going to give up because I believed my life depended upon it. For most people, 2-3 years you can expect the changes you want. If you are really in tough shape it may take longer but that should not deter you. I love patients who bring big challenges. They are the most appreciative patients I have had in the last 5 years. We can never settle for a C or D when an A is possible.

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Please Note: The author of this site is not engaged in rendering professional advice or services to the individual reader. The ideas, procedures, and suggestions contained within this work are not intended as a substitute for consulting with your physician. All matters regarding your health require medical supervision. I shall not be liable or responsible for any loss or damage allegedly arising from any information or suggestions within this blog. You, as a reader of this website, are totally and completely responsible for your own health and healthcare.