Quantum Biology 10: Hormones 102

Two years ago I gave you the Hormone 101: Clinical thoughts revealed blog post. That was a small dose of reality at the beginning of this journey. There was some foundational hormone biochemistry there given to you in simple terms. Most people jumped all over the free T3 link to pregnenolone in the post. They thought that “their cure” for hypothyroidism and/or chronic pregnenolone steal syndrome was increasing free T3 or just lowering reverse T3 to raise pregnenolone. So what was not observed?

A trip down memory lane for the hormone cascade

Leptin resistance occurs first in the brain. Then insulin resistance happens soon their after in the liver, gut, and peripheral tissues. This eventually leads to adrenal resistance. This resistance occurs at the PVN in the brain. (Brain Gut 16: Adrenal Fatigue Rx) It does not happen in the adrenal gland. What happens is that the outflow from our sympathetic system in the brainstem overwhelms the parasympathetic nervous system. This increase in overall cortisol initially, is the stress hormone that allows for fight or flight syndrome (life or death). As this condition persists chronically over time, cortisol levels decrease and flatline on adrenal stress index testing.

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CPC #6: Pseudotumor Cerebri

It has been close toa year that we last did a CPC blog post. (CPC #5 The Leaky Gut/Adrenal Fatigue Case) CPC stands for a clinico-pathologic conference that we often see in medical schools that our used for teaching students and doctors.

Today we are going to talk about a disease that has perplexed medicine for hundreds of years. Pseudotumor cerebri is also known as idiopathic intracranial hypertension (IIH) today. It goes by many names in the literature. I have decided to discuss this disease because it highlights many of the cornerstone principles of how quantum electrodynamic theory affect water chemistry. This change in water chemistry can lead to biologic effects. The biologic effects of water can be seen in modern humans when we look for them and correctly observe what is really going on. So today we see how the macrocosm affects the microcosm of a modern disease.

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Quantum Biology 9: Photosynthesis

Life is energy. All life is tied to our sun. The sun powers everything with the photoelectric effect. Today, you are going to see how this quantum effect makes life dance.

To synthesize simple carbohydrates from sunlight requires 30 proteins to work together in a cell membrane. Research into the mechanism of photosynthesis centers on the understanding the structure of the photosynthetic components and the molecular processes that use radiant EMF energy to drive carbohydrate synthesis. The research involves several disciplines, including physics, biophysics, chemistry, structural biology, biochemistry, molecular biology and physiology, and serves as an outstanding example of the success of multidisciplinary research. This process should give us a clue that systems thinking about problems could solve many modern mysteries.

In our universe, and in all life forms, energy’s primordial state is not rest. Energy does not like to sit around like a couch potato. If you do sit around often like this, this is a quantum sign that you are losing energy in the forms of electrons, photons, phonons, and protons to you own environment. Today’s blog is on the quantum biology of energy dynamics. In the universe, as there is in things living energy is always present. The key factor, however, for life is the amount of energy in its therapeutic dose. A body without energy is called a cadaver. A body with a lot of energy is like a trendy party animal. Energy propels our planes, trains and automobiles to move, and it keeps us warm, grows our food, and helps us see the world we live in.

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March Webinar: The EMF Rx

March Webinar: The EMF Rx. There are so many gems in this webinar.  Together, we’re going to connect some pretty important dots to help you on your road to optimal. Why people on the Paleo diet often experience increased constipation How fluoridated water is causing DEHYDRATION, and how dehydration is at the root of all sorts of neolithic diseases, in a sense, making them chronic because syndromes persist when you’re in a dehydrated state How fluoridated water weakens the blood-brain barrier, allowing toxins normally excluded from the brain’s circulation to enter (Dr. Kruse believes fluoridated water to be the #1 cause of leaky gut in our modern world) How high LDL cholesterol levels are tied to hypothyroidism How EMF exposure is tied to increased cancer risks, childhood leukemia, headaches, “aging” diseases like Alzheimers and dimentia, and other disorders How children’s brains are affected by pulsed EMF – DANGEROUSLY Why LDL levels rise so often with a Paleo diet Why the HCG diet works in many men and women This webinar is rich with content, and Dr. Kruse is going to review the three main legs to the stool for creating optimal health — they’re simple, yet profound, and could very well give you the breakthrough you’ve been looking for to super-charge your quest […]

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EMF Rx: The Top Ten EMF FAQs

Soon the EMF Rx will go live in our March 2013 webinar so in advance of it, I wanted to give the EMF FAQ’s for everyone to review before you listen to the webinar. I expect there to be many questions once the webinar is released. Hopefully this will answer many of the questions you might have as the series moves forward.

These may make a lot more sense once you listen to the EMF Rx in the webinar. They will really sink in after you hear our EMF expert that we are bringing on to the site for an extensive long term look at the different aspects that EMF causes in our modern world, but here is an appetizer of what is coming.

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Quantum Biology 2: Quantum PCOS

Who is Gretchen? She is a women I met at Mark’s Daily Apple monster thread two years ago. When we first met she wanted no part of the idea that maybe she was missing more pieces to the puzzle then she knew. I told her back then, if she began to test herself she would learn more about herself than she could ever imagine and it would happen fast. If you read the thread here, you will see where she began her journey. This blog is where her journey has brought her in her battle to reclaim optimal. She is also featured in my latest book on amazon, The Epi-Paleo Prescription and you can read her initial six months into this journey there with 3 other of my members. Gretchen has a blog too. She is a pretty amazing person with an amazing family and story.

Here is how her journey began as written and told by award winning author Colleen Coble in my book:

Gretchen stared at the piece of paper in her hand. The word medically discharged wavered in her vision, and she wheezed through the airways constricted by asthma. Her head was pounding, and her heart rate fluttered even faster than the pulse of pain in her head. It was the end of her military career. Even though she’d known it was coming, seeing it in black and white made her want to sink to the floor and bury her head in her head in her hands.

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EMF 7: Quantum Prometheus

If you remember my podcast several years back, I told you the disease that got me interested in all this was osteoporosis. This is a disease I treat a lot as a spine surgeon. I discussed Wolff’s law in detail in the EMF 1 blog. When I realized that Wolff’s law was null and void in leptin resistance states in bone, something else radical appeared to me. I knew that Leptin Resistance signaled inflammation, and inflammation could be seen as a positive charge and loss of a negative charge on MRI’s, fMRI, and MEG studies. I also realized that MRI or NMR should show an increased flair signal on T2 weighted MRI images signifying an intracellular water loss coupled with a loss of collagen and of ATP. Collagen makes up the main protein of connective tissues in all mammals, typically 60–70% by weight. The water and collagen constitute a liquid crystalline matrix in which every cell in the body is embedded, making this system the ideal medium for intercommunication in eutherian mammals. Within this matrix we have learned about proton and electron superconduction that not only feed the underlying mechanistic pathways that most biochemistry recite but they also feed a rich “wet chemistry” that is fundamentally based upon special qualities of water. It turns out water has some prodigious quantum flexibility when it is confined in closed spaces that make it do some unique quirky things that no classic chemist would predict. These things are all predicted by quantum electrodynamic field theory. One such quirk is the use of water reverse micelles around proteins that increase enzyme action and kinetics by the order 10 to the 10th power based upon the pioneering work of Frank Mayer and Jim Clegg. Classic physics and chemistry thinks of water in its bulk form only because that is all the classic sciences can explain about it. In quantum coherence, where water acts as a total cohesive unit because it has infinite chemical freedom, water becomes highly structured chemically, from its bulk form to do some amazing things, to become extremely flexible in phase transitions between ice crystals and liquid crystals and gas vapor as it gets confined in small diameter nanotubes in our cells. Water dynamics and actions are quantumly altered as it is confined within nanotubes it develops properties that allow it to collectively work dynamically within reverse micelles and in proton superconducting cables that align along collagen in the cells cytoarchitecture to allow for super fast semiconduction. This has been reproduced by many physics and molecular biology researchers in electron photomicrographs and X-ray diffraction studies. The most amazing property water develops as it is confined in these nanotubes, it becomes a super catalyst that organic chemistry has missed, because it accounts for the energy of activation of biochemical reactions and enzymatic kinetics. It is not ATP that does this, ever!! ATP has another more critical function. It unfolds protein in cells to open water binding sites to form these super conduction cables to create 100% energy efficiency.

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EMF 4: Why Might You Need Carbs for Performance?

Today EMF-4 is going to hit a very controversial topic. Why do the younger performers perceive they need carbs for performance? For years, I have said loudly, I don’t believe it is true. Over the last 7 years I have begun to understand why their belief exists now. When you suffer from a disrupted circadian clock you perceive you do need carbs.

It has been shown recently that artificial EMF’s make our blood brain barrier and gut more permeable to carbohydrates. The micropulsations of EMF control biocycles, including the timing of mitotic rhythm and the entire cell cycle. Any major change in their frequency would be catastrophic for cells. In fact, today most of the paleo-sphere is unaware that experiments already have been done that have shown that vibrational rates near normal and slightly above the Schumann resonance, from 30-100 Hz, cause dramatic changes in the cell cycle timing.

It turns out, the most powerful shaper of our development may turn out to be the subtlest force, that is completely invisible to us and perturbs the manner in which we handle macronutrients and recycle ATP.

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EMF 2: Einstein, Meet Leptin

“You’ve got to work at living… when 99% of the globe works at dying daily; Denial of the truth will lead you into blind alleys. Let go of your paradigm, accept what nature designed, and embrace your ultimate potential” -Gretchen Bronson (starfish)
Why is the clock the most important part of the story of life?

Have you ever had a dream that seems so large in scope, it just seems like it just possibly cannot come to fruition? I have for the last 7 years. Today, I am going to share it with you.

It is time. I believe all dreams come true, if we have the courage to pursue them. It is always easier to make a dollar off a dream, but it is a lot tougher to make a difference with one. I think EMF-2, is going to do just that for everyone.

I told you all last March, on Sean Croxton’s underground internet radio show, and at Paleo FX 2012, that environmental mismatches all cause inflammation. Many of you found it a bold and interesting statement, but I never told you WHY. The reason I did not, was because I did not feel you were ready to understand my perspective, yet. Today that changes. When you do not understand someone’s perspective often times what they say sometimes sounds a bit ‘bizarre’ to you. The reason it does is because you have no frame of reference for understanding, primarily because you were never taught that space/time, might be the most critical factor in understanding trans-generational epigenetic biology today. That is going to change today as well.

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BRAIN GUT 17: THE POWER SQUAT

Today we are going to talk a bit about your “out door” as part of the brain gut series continues.  Today I am going to show you how spinal biomechanics and defecation are intimately related to good or poor physiologic function and may result in illness.  The human spine has 5 lumbar verterae and one block of bone distal to it called the sacrum.  The sacrum forms the back bony wall of the pelvis. 

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THE DOPAMINE Rx = GOOD CHOICES OR BAD

We learn best when we move through our environment. Moving naturally is how humans learn best. This is why even those stricken with severe Alzheimer’s disease tend to improve cognitive performance with even mild exercise. Natural movement stimulates cortisol which increases neuron growth in our hippocampus to increase our ability to learn. Neural science tells us this and it is proven in how humans act and react to environmental stimuli to learn.

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BRAIN GUT 12: DARE TO DISAGREE?

READERS SUMMARY: 1.  IS NUTRIENT DENSITY FROM A USDA CHART IMPORTANT IF IT IS OUT OF CONTEXT FOR THE SPECIES IN QUESTION? 2. PALEO SAYS PUFA’S ARE BAD.  ARE THEY REALLY; OR IS OUR UNDERSTANDING OF THEM LACKING? 3. WHY IS IODINE A CRITICAL FOR A HUMAN? 4.  IS GETTING A HASHIMOTO’S DIAGNOSIS LIKE GETTING A CANCER DIAGNOSIS? 5.  DO WE HAVE A GIANT PHARMACY IN OUR HEAD? We recently heard about nutrient density in the Brain gut 5 blog.  It seems all of a sudden it has become a hot topic in the paleosphere too now.  The one issue however that is not well understood or talked about enough in my opinion is putting this key factor in proper evolutionary and scientific context.  When someone uses the FDA and USDA massive databases to look at foods with the highest nutrient densities to make large assumptions what is best and what is not, you might be smart to begin to question if that is a wise assumption to begin with.  Let me explain.  The tables are measuring nutrient density of foods against other foods and not against the species of animals eating those foods.  What it does not do is taking into […]

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BRAIN GUT 11: IS TECHNOLOGY AN ACHILLES HEEL?

READERS SUMMARY:   1. A QUESTION DURING AN EDUCATIONAL CONSULT STIMULATES A DISCUSSION 2.  HOW DOES ARTIFICIAL LIGHT DESTROY THE SIGNALING OF THE CORTISOL/DHEA/MELATONIN AXIS? 3. HOW DOES ARTIFICIAL LIGHT AFFECT  THE GUT FLORA? 4.  CAN ARTIFICIAL LIGHT AFFECT HUMAN BIOLOGY DIRECTLY? 5.  IS BODY COMPOSITION TIED TO ARTIFICAL LIGHT AND IMPAIRED SLEEP CYCLES?     Question asked to me during an educational consult: I still don’t understand the significance of the prolactin surge especially in older people like me. Since I am post menopausal, what happens if I eat carbohydrates within 4 hours of going to sleep? What does it have to do with leptin resistance? I am neither a science person, so is there any way to explain it in less technical terms?     BEFORE WE BEGIN TAKE A LOOK HERE AND TELL ME IF YOU THINK EVOLUTION HAS A PLAN FOR THIS?   I hope everyone realizes that artificial light has only been around on our planet since 1924.   Just so we are clear. Chronic artificial blue light is equivalent to chronic excessive carbohydrates because both contain excessive photoelectric energies.  This alters mitochondrial functioning after a period of time because our mitochondria evolved expecting a […]

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Brain Gut 9: What Really Killed Michael Jackson

Today, we are going to dive into the gut flora story a bit deeper than we did in our first gut flora post to help you understand how a a change in gut flora might lead to changes in your health by altering your hormone panel. Obesity is an inflammatory brain condition. Where does the infection come from? The gut flora actually is what causes humans to become fat. It has to due with shear numbers and the species of bacteria in our gut. There is a particular flora that produces adiposity and obesity in humans. These bacteria make something called FIAF (Fasting induced adipose factor) that control this process. This factor blocks lipoprotein lipase (LPL) in fat cells. LPL allows us to convert dietary Free Fatty Acids carried in lipoproteins into neutral fats that are stored in adipocytes.

Non Geeks: Our gut bacteria makes humans fat.

Geek Alert: The FIAF is made by our liver, muscles, and our small bowel wall when food sources are in short supply. This is the signal to stop storing fat in our fat cells when food is scarce. What is not well appreciated by many is that the FIAF in our intestinal wall is controlled 100% by our gut flora. When we have a simplified gut flora it favors fat cell creation. When our gut flora is complex and healthy, it has 100 trillion cells with 250 species. We tend not to make fat in this instance either! Moreover, when the bacteria are active metabolically due to the presence of simple sugars, production of FIAF ceases, and fat creation is signaled. This implies that our gut flora is directly tied to fat creation in humans. The gut flora’s action is directly signaled to the brain via the afferent nerve fibers in the vagus nerve. In those newly created fat cells, a protein called leptin is also produced, and acts as a score keeper for the brain of how much fat is stored in the body. This messenger is sent to the brain around midnight when we are sleeping allowing the brain to assess total energy balance in the body.

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Brain Gut 6: Epi-Paleo Rx

This blog followed a very popular July 2012 Webinar that I put on for my members a few days ago. The webinar was over two hours long and had a lot of Q & A done after it as well. I promised my members I would get a quick blog post up for them on some of the core materials we covered. Today’s blog is delivering on that promise.

How to consider eating the Epi-Paleo Rx: Always Respect circadian cycles and eat according to seasonality, Lots of good quality proteins (see below), Lots of good quality fats (grass-fed/pastured animal fats – lard, tallow), Liberal uses of seafood broths and bone broth made from ocean and grass-fed animals (to heal the gut), and fermented vegetables and/or probiotics (to repopulate the gut with an Optimal Human flora)

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Brain Gut 5: Paradigm Drifts Paradigm Shifts–Epi-Paleo

Geeks: The implications of Brain Gut 4 mean that to develop a brain seafood is required part of the program to maintain it. Nutrients and many other environmental factors have also been found to influence epigenetic programing of our DNA either directly or indirectly via metabolic sensors. Peroxisomal proliferator-activated receptors (PPAR’s), the vitamin D receptors, and the retinoid X receptors (RXR), and the retinoic acid receptors (RAR) are all examples of the nuclear receptors that interact with the brain cell membranes to control inflammation and metabolism all over our bodies. It turns out that PPAR’s are the receptors that are at the crossroads of where inflammation and metabolism actually cross. These are specialized lipid sensors that pay attention to our balance of omega 6 and 3 levels. 3% of the human genome is directly or indirectly controlled by the endocrine functions of the Vitamin D system. This shows you how environmental signals are intertwined into the expression of DNA in humans. The Epi-Paleo Rx controls inflammation at a hormonal level in the brain better than the more famous paleo diet.

Non Geeks: What we eat is really damn important when you have 3 lbs of lipid in your head called a brain. If you eat outside our design you get sick.

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Brain Gut 4: What was Homo’s Solution?

The paleo community has the “Paleo Solution”, and it is a great introductory book to a lifestyle that will improve people to a higher plane of health than we have while eating a standard American diet found in our western world. It is clear from fossil data humans were in better physical shape in the late paleolithic before the Younger Dryas occurred as well. It appears that this deep freeze caused massive dietary change in the homo species from predominate hunter gatherers culture to and agrarian culture because of rapid climate change and elimination of the great megafauna from our food chains. The focus of this series, however, is focused upon when we jumped from purely primate to mainly homo species and to see what diet is really best for the rapid encephalization of our species. I am not convinced the modern paleolithic diet that is quite popular now fits that bill at all. The reason I bring this forth, is because I treat very sick and ill homo sapiens every day. ‘Eating paleo’ may just not reverse their health. The proof of this is found on every single popular paleo forum you can visit. As a surgeon, I need something that really works in the most resistant cases. That is where I discovered the Epi-Paleo Rx.

In my specialty of spine surgery, this is especially true when we are dealing with cranial and spinal pathology. As a neurosurgeon these neolithic diseases are the ones I am most focused in on in my clinic. Evolution is in large part about epigenetic to cellular communication; it’s comparing notes and copying and pasting new genetic recipes to create a new dish. When we understand how that dish was created we gain deep insight of how to to keep that dish tasting crisp and fresh every time we replicate it.

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Hormone CPC #1: DHEA

This blog post was created for my members who just heard my webinar on bioidentical and synthetic hormone replacement. It is specifically designed to further our discussions in that talk.

DHEA has been an enigma to the public and to most physicians. I never once heard about this hormone in four years of medical school, seven years of residency or in any endocrinology lecture from my training. The general public did not learn about DHEA until 1996, when its benefits were mentioned in the media and several popular books that showed up on daytime TV shows. Most in mainstream medicine continued to ignore the science these books contained because they were not found in the usual ways via journals and continuing education classes. You actually had to be on the lookout for this information. With a busy medical practice, this is no easy task. DHEA became credible to the medical establishment when the New York Academy of Sciences published a book called DHEA and Aging. That book provided scientific validation for the many life-extending effects of DHEA.

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Cold Thermogenesis 6: The Ancient Pathway

The best way to describe this pathway to the lay public is to explain this is how evolution allows for ideal form to meet function in a tough environment. This environment is likely the primordial environment for life on our planet. This makes astrophysicists excited, because life might also be evolving in places like Titan. After all 5 extinction events on this planet geologist have told us they were followed by an extended cold climate. In cold mammals live longer. You will find out more about why this happens in Energy and Epigenetics 4 and 5 blog posts.

The pathway uses very little energy from ATP and gives a whole lot to the organism who uses it. Fat burning is required and it is tied to a biochemical pathway that paleo forgot to speak about. But it requires cold temperature to be present and used commonly. In the pathway, the less effort you give, the faster and more powerful you will be when this pathway is active. People who live in this pathway can run a marathon with no training. They can lift unreal amounts of weight with little training. Their reserve and recovery are just incredible. You have to see it to believe it. Many will say cold thermogenesis a hormetic process, when in reality it is created using a coherent energy source due to something called the Hall effect. When we have had extinction events on Earth before, the events usually affect the evaporation of water in some fashion from the surface of lakes and oceans. It also affects the transpiration from the forest trees, plants, and flowers and this change cools the air. You must understand how climatology works here; liquid water needs to absorb a lot of latent heat to in order to evaporate, so it sucks energy from the atmosphere to make this energy transfer. This loss of energy from the atmosphere directly cools the planet and this preserves the charge on life’s inner mitochondrial membrane and in the nanotubes present in our cells that contain water. This is how life lives long in the cold.

Those people don’t realize this because they do not live in this pathway for the majority of their life, and few studies have been done to say otherwise. The link above is recently added to this blog post. It seems science is now proving me correct in my theories of extinction events.

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Cold Thermogenesis 4: The Holy Trinity

I just want to thank Sean Croxton for asking me to present at Paleo Summit today. The ideas discussed began with a podcast I did with Jimmy Moore, #474. Before I begin here today, I strongly suggest you listen to the Jimmy Moore podcast I did in May of 2011 as a primer for this blog post. It’s going to be a long one, so open a glass of wine as the sun sets tonight. However, I think you need to hear it all tonight since I have your attention from the Paleo Summit. I have planned for this day for some time. I am humbled to share this with you all. It was hard for me to write.

If any of you remember when I first gave my initial thoughts on leptin publicly, it was on a podcast I did with Jimmy Moore in May 2011. I discussed the things that transformed my thinking back then. Most of the time I spent with Jimmy, we talked about leptin. In the beginning of the podcast, I mentioned a person who saw me injure myself as I stood up to give a lecture, and told me she knew precisely why I hurt my knee. At the time, I thought I had a good handle on these modern medicine principles she mentioned so I was a skeptical of her thoughts. She told me when I got home she was going to send me a few papers and a book to read. The book was called “The Monk Who Sold his Ferrari.” She was emphatic that I read the book before the papers. Then, she told me to read six specific papers in the order they were numbered and then reflect on what I had just read.

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