30 Things from the Innovator’s cocktail party

READERS SUMMARY: 1.  Those that came to this party I had in June 2015 requested I publish this note I gave all attendee’s for the public to see.  Your wish is my command.   To be yourself in a world that is constantly trying to make you something else is the greatest accomplishment. I am only one, but I am one. I cannot do everything, but I can do something. And because I cannot do everything, I will not refuse to do the something that I can do.   30 things that I began in 2010 to cross off my bucket list 1. I want to step foot on every continent. 2.  I want to feel sustained zero gravity sans water 3. I want to climb another pyramid. 4.  I want to climb the Great Wall of China 5.  I want to spend a long weekend in an ice hotel 6.  I want to make a difference in my world, by changing your world. 7. Develop the practice of medicine based on nature’s quantum principle’s 8.  Build the perfect quantum isolation chamber for wellness 9.  Paint my electrons on a canvas 10.  Learn to play the piano 11.  Have my […]

Continue Reading


READERS SUMMARY: 1. HOW DO PLANTS DO WHAT HUMANS FAIL AT? 2. HOW DOES OUR SKIN, EYE, AND GUT DETERMINE WHAT HAPPENS IN MITOCHONDRIA? 3.  WHAT REALLY CAUSES CONSTIPATION ?   4. HOW DOES LIGHT MAKE WATER A LASER?  5. HOW DOES THIS EXPLAIN LEPTIN RESISTANCE? In Ubiquitination 21 we began to talk about how plants connect to their environment 100% of the time to generate their energy free of food using water and sunlight and CO2 from the air as their major source of carbon. HOW DO PLANTS CONTROL THEIR GROWTH PROCESS? Plants and trees differ from animals because they can’t move fast across tectonic plates.   Movement creates a much larger “GPS timing” problem for animals that plants and trees don’t have to face. Plants put in these type of fast growth and high light environments (ex: a magnolia tree) adapt the position of their leaves by inclining their leafs away from the sun and reflecting the incoming solar radiations to avoid higher temperatures.  Also note how the outermost leaves are dehydrating and browning because they cannot overcome the 102 degree temperature today with stomatal conductance.  Note the leaves close to the bark are quite green and healthy. […]

Continue Reading


READERS SUMMARY: 1.  HOW DO PLANTS AVOID CANCER? 2.  WHY DO WE GET IT? 3. WHY DON’T WILD ANIMALS GET CANCER? 4. WHY ARE ANIMALS IN CAPTIVITY SUSCEPTIBLE TO CANCER? 5.  IS FOOD AND EXERCISE ALL ITS CRACKED UP TO BE, OR IS IT LIGHT?    Let us quickly review why is the bending of blue light a modern problem? It has massive implications of how fast or slow the circadian clock in the central retina operates. It is driven by blue light detection via melanopsin. These neurons project directly and exclusively to the suprachiasmatic nucleus (SCN). Light synchronizes mammalian circadian rhythms with environmental time by modulating retinal input to the circadian pacemaker— SCN of the hypothalamus. Such photic entrainment requires neither rods nor cones, which until very recently, they were the only known retinal photoreceptors. We covered the details of the eye clock earlier in this series. Today, we know that retinal ganglion cells innervating the SCN are intrinsically photosensitive. Unlike other ganglion cells, they depolarized in response to light even when all synaptic input from rods and cones was physically blocked. Their sensitivity, is tied to spectral tuning by the frequency of light. Because blue light bends more […]

Continue Reading


READERS SUMMARY: HOW DOES LIGHT LINK PLANTS AND ANIMALS? WHAT ARE THE DEEP BIOLOGIC IMPLICATIONS IF THAT SYSTEM IS AWRY? CAN ARTIFICIAL LIGHT ALONE EXPLAIN DISEASE AND PSEUDO-HYPOXIA?   The Earth’s environment is a 24/7 factor that plants and animals have to deal with. Every single minute of the day we have the chance to be exposed to various spectrums of natural or artificial  light or total darkness if we do sleep correctly. Plants eat sunlight and drink water for their food. Compare that to eating food for animals. Humans may spend an hour, in total eating meals. Have you ever wonder which matters more, light or food? Plants don’t need food because the use light and CO2 from the thin air to make sugar. Humans properly connected to light cycles and Earth who have their energy generating mitochondria coupled to nitrogen cycles don’t need a ton of food to live either. We have the ability to run for long periods of time using the part of the our mammalian battery that uses photosynthesis exclusively.   Food is not the man driver of ubiquitin marking for protein recycling in humans. It maybe your opinion or a current belief, but it […]

Continue Reading


READERS SUMMARY: IS NITROGEN SUNLIGHT’S BRAKE? HOW DOES PORPHYRINS SLOW DOWN LIGHT TO MAKE ENERGY USABLE TO LIFE? IS SURFACE CHEMISTRY MORE IMPORTANT THAN BIOCHEMISTRY WITHIN A CELL? WHAT IS A FLUOROPHORE OR A CHROMOPHORE AND HOW DO THEY USE LIGHT? WHY DOESN’T VITAMIN D3 HAVE NITROGEN IN ITS MOLECULAR STRUCTURE?     On Earth most of our atmosphere is made up of nitrogen.  78% of it, to be exact. It turns out that sunlight’s interaction with this massive amount of nitrogen surrounding us constantly is the first step in how life below is able to harness the sun’s energy to make it usable for life. When sunlight first hits nitrogen high up in the atmosphere it generates an air-fluorescence radiation. Fluorescence is the emission of light or electrons by a substance that has absorbed light or other electromagnetic radiation. Sunlight makes nitrogen emit radiation in the UV range. Air-fluorescent radiation is capable of generating secondary electrons from this initial interaction. These interactions are very difficult to control, as most particle physicists can attest too. Most of these emitted electrons from nitrogen within our magnetosphere are low energy electrons ≳1 keV. The magnetosphere block most of the higher energy photons […]

Continue Reading


New study came out in the media this AM and caused a lot of phone calls asking for an opinion:  The study was on microwaving foods on kids health.  Was microwaving safe in plastics adjacent to foods?  Will the chemicals be photo-bleached into their food and show up in their urine.  If it enters their urine might they get a kidney based symptom or disease?    The FDA does regulate what plastics can be used in microwaveable foods so this was the reason the study was done.   This apparently was just talked about on Today show this AM so this is why it caused a stir in my office this AM. This story was about the effect of microwaves having the physical ability to liberate BPA and phthalates from the plastics and photo-bleach them into the foods.  This is an alert for parents and  kids:  the study was  correlated to lead to hypertension in kids.  Note: causation was not the end variable of the design.  The fact that they found hypertension in a population who does not have this is more interesting when you understand the science of how microwaves work physically.   How might that be? Let us […]

Continue Reading


READERS SUMMARY: HOW DOES LIGHT COUPLE TO NITROGEN TO DETERMINE CARBON FLOWS IN ANYTHING ALIVE? HOW DO EXTINCTION EVENTS SHOW US NITROGEN CYCLES ARE THE KEY DRIVERS OF THEIR PRESENCE? HOW DOES COLD PLAY A KEY ROLE IN YOUR QUANTIZED ECOSYSTEM? DO UBIQUITIN RATES LINK TO THE AMOUNT OF ELECTROMAGNETIC RADIATION IN THE ECOSYSTEM? IS MY ZIP CODE MORE IMPORTANT THAN MY GENETIC CODE?   I just returned from a meeting with my members in the Chicxulub crater and spoke about how the crater links humans to their modern ecosystem.   What connects them is their mitochondria.  I spoke about this deep connection in my book, The Epi-Paleo Rx.  You might have missed how this crater directly coupled life on Earth today with a huge environmental shift that occurred 65 million years ago.  The two major groups of life that survived this environmental event had  excessive mitochondrial capacity in their body plans.  This was the key requirement for life to survive post event.  Photosynthesis was disrupted for a long period of time so it meant that life had to live on the edge, using this capacity to survive in some way.  Light normally flows from the sun to living things on […]

Continue Reading


AUSTIN SPEECH OUTLINE: June 20, 2015    9:18 AM Look around you…..what do you see.  You see a lot of blue light on this stage.  It looks really neat but have you ever asked yourself can “neat” hurt you? My name is Jack Kruse and I came here to engage you, and to help you flourish. I don’t build businesses in my world. I build people. To flourish, and sustain flow, you must taste failure. We learn best, from our own failures, if we are wise. So let me tell you a bit about my own failure. Ten years ago I was morbidly obese because of the environment I allowed. Where I found my change was not where most people look. I was at the foot of Michaelangelo’s David and looked up at perfection, and then down at me……..I was 360 pounds of failure at 40 years old. I asked myself: “what is the difference between David and myself? The answer was simple…………. the environment we both lived in was radically different. On the plane home, I wrote two prescriptions for myself called the Leptin Rx and the Cold Thermogenesis protocol. One was based upon light signaling in the brain and […]

Continue Reading


READERS SUMMARY: 1. WHY IS MELANOPSIN IS THE PHOTORECEPTOR OF THE EYE CLOCK? 2.  DO ALL PHOTORECEPTORS NEED DHA TO OPERATE? 3.  WHERE DID VISION COME FROM, LAND OR SEA? 4.  WHAT DOES OPTIMAL SIGNALING PROVIDE TO A CELL? 5.  WHAT CONTROL CELLS MOST, DHA, GENES, OR MITOCHONDRIA?   Today we start out with a lot of science but quickly we stop the deep science to explain to you how the eye clock gears work in your mitochondria. The summary offers you a simplified version of what optimal really is.   Do not die while you’re still alive. An elevated ubiquitin rates allows that to happen. Oysters are a kiss from the sea that prevents the kiss of death from visiting you too early.   Let us dive in and see why………… Several studies have established that the retina is the only tissue capable of visual and non-visual photoreception in mammals. Therefore, it appears the retina plays a vital role in circadian organization of the whole organism. Within the mammalian clade their is variability due to the levels of docosahexaenoic acid (DHA) that are used in the complexity of the eye’s clock. The essential omega-3 fatty acid family member is […]

Continue Reading


READERS SUMMARY: 1.  IS YOUR EYE A CAMERA OR CLOCK? 2.  HOW DOES NEGATIVE FEEDBACK CONTROL RUIN YOUR CLOCK? 3.  IF TIMING IS OFF IN YOUR EYE,  DO DISEASES SHOW UP OUT OF THE BLUE? 4. ARE CATARACTS AND GLAUCOMA A PREMONITION OF ONCOGENESIS? 5.  HOW MUCH ATP DOES PROTEIN SYNTHESIS COST A CELL?   Your eye can be a clock or a camera. A blind man’s world is bounded by the limits of his touch and he relies on his timing; an ignorant man’s world by the limits of his wisdom; a successful man’s world by the limits of his vision and sense of timing. Man is the most complex eukaryote. Therefore he has the most sophisticated time piece in his eye that controls protein turnover. Protein turnover is a synonym for ubiquitin marking. Eukaryotes spend 80% of their total energy budget on protein synthesis. That process is controlled by ubiquitination rates in cells. This is why you need to understand ubiquitin. Once you master ubiquitin you can use that recovered energy to reverse illnesses. Each peptide bond requires 5 ATP to seal the bond. That amount is 5 times as much that is needed to polymerize nucleotides into […]

Continue Reading

What Others Are Saying

Many months ago, I was asked by someone to do a video testimonial for jackkruse.com. I planned to do it when I lost my last two pounds to my 50lb goal. Little did I know that would be 9 months later!

Take a listen to this story from Rob Hamilton. His story attests to the power of living Optimally.

Please Note: The author of this site is not engaged in rendering professional advice or services to the individual reader. The ideas, procedures, and suggestions contained within this work are not intended as a substitute for consulting with your physician. All matters regarding your health require medical supervision. I shall not be liable or responsible for any loss or damage allegedly arising from any information or suggestions within this blog. You, as a reader of this website, are totally and completely responsible for your own health and healthcare.